NBS-C BioScience
RECENT PUBLICATIONS
Determinants of interactions of a novel next-generation gabapentinoid NVA1309 and mirogabalin with the Cavalpha2delta-1 subunit.
Souza I, Gandini M, Ali Y, Kricek F, Skouteris G, Zamponi G.
Molecular Brain (2024) 17:54
Germline BARD1 variants predispose to mesothelioma by impairing DNA repair and calcium signaling.
Novelli F, Yoshikawa Y, Vitto V, Modesti L, Minaai M, Pastonino S, Emi M, Kim JH, Kricek F, Bai F, Onuchic J, Bononi A, Suarez J, Tanji M, Favaron C, Zolondick A, Xu R, Takanishi Y, Wang Z, Sakamoto G, Gaudino G, Grzymski J, Grosso F, Schrumpi D, Pass H,Atanesyan L, Smout J, Sarin K, Abolhassani H, Hammarstrom L, Pan-Hammarstrom Q, Giorgi C, Pinton P, Yang H, Carbone M.
PNAS121 (29), 2024: 1-12.
A next generation periperally restricted Cavalpha2delta-1 ligand with inhibitory action on Cav2.2 channels and utility in neuropathic pain.
Kricek F, Ruf C, Meghani P, Souza I, Gandini M, Zamponi W, Skouteris G.
Biomedicine & Pharmacotherapy 174(2024) 116472
Novel aryl sulfonamide derivatives as NLRP3 inflammasome inhibitors for the potential treatment of cancer.
Albanese V, Missiroli S, Perrone M, Fabbri M, Boncompagni C, Pacifico S, De Ventura T, Ciancetta A, Dondio G, Kricek F, Pinton P, Guerrini R, Preti D, Giorgi C.
J. Med. Chem 2023, March 27; 66, 7: 5223-5241
A Small Contribution to a Large System: The Leptin Receptor Complex.
Jennifer M Simien, Grace E Orellana, Hoa T N Phan, Yao Hu, Emily A Kurth, Christine Ruf, Franz Kricek, Qian Wang, Alan V Smrcka, Ellinor Haglund
Journal of Physical Chemistry. B 2023 March 14
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment.
Missiroli S, Perrone M, Gafà R, Nicoli F, Bonora M, Morciano G, Boncompagni C, Marchi S, Lebiedzinska-Arciszewska M, Vezzani B, Lanza G, Kricek F, Borghi A, Fiorica F, Ito K, Wieckowski M, Di Virgilio F, Abelli L, Pinton P, Giorgi C.
Cell Death Differ. 2023 Feb;30(2):429-441
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants.
Monteil V, Eaton B, Postnikova E, Murphy M, Braunsfeld B, Crozier I, Kricek F, Niederhöfer J, Schwarzböck A, Breid H, Devignot S, Klingström J, Thålin C, Kellner MJ, Christ W, Havervall S, Mereiter S, Knapp S, Sanchez Jimenez A, Bugajska-Schretter A, Dohnal A, Ruf C, Gugenberger R, Hagelkruys A, Montserrat N, Kozieradzki I, Hasan Ali O, Stadlmann J, Holbrook MR, Schmaljohn C, Oostenbrink C, Shoemaker RH, Mirazimi A, Wirnsberger G, Penninger JM.
EMBO Mol Med. 2022 Aug 8;14(8):e15230. doi: 10
BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos.
Novelli F, Bononi A, Wang Q, Bai F, Patergnani S, Kricek F, Haglund E, Suarez JS, Tanji M, Xu R, Takanishi Y, Minaai M, Pastorino S, Morris P, Sakamoto G, Pass HI, Barbour H, Gaudino G, Giorgi C, Pinton P, Onuchic JN, Yang H, Carbone M.
Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2111946118.
The Peptide TAT-I24 with Antiviral Activity against DNA Viruses Binds Double-Stranded DNA with High Affinity.
Harant H, Höfinger S, Kricek F, Ruf C , Ruzsics Z, Hengel H, Lindley I.
Biologics 2021, 1(1), 41-60Type your paragraph here.